Chicken Spaghetti with Rotel

Chicken spaghetti with rotel and cheddar cheese has something for everyone to enjoy. Tender spaghetti in a creamy cheddar sauce with chunks of chicken. A hearty dinner the whole family will love.

Next time, try this creamy pasta bake so delicious and so creamy.

Save this recipe by clicking on the ❤️ heart on the right-hand side of the screen or in the recipe card.

This is our favorite family go-to pasta casserole. The kids gobble it down in no time and always ask for seconds. Experience this unforgettable combination of pasta and chicken in a yummy sauce. A pasta dish where cheesy sauce is clinging to each strand of spaghetti. This is one sensational meal that always pleases.

Jump to:

• Chicken spaghetti casserole
• Ingredients you'll need
• Before you begin: essential tools
• Step by step: instructions
• Adaptable recipe – make it your own!
• My notes
• 💬 FAQs
• Make Ahead
• What to serve with Spaghetti Chicken
• Storage and reheating
• More comfort food recipes
• For my chicken lovers
• Chicken Spaghetti

Chicken spaghetti casserole

• A kid-friendly dinner that also feeds a large family.
• This cheesy chicken spaghetti with Rotel diced tomatoes and green chilies is as perfect the next day.
• Quick and easy casserole with few ingredients and full of cheesy goodness.
• The best make-ahead classic comfort food, a great recipe for a friend.

Rotel Chicken spaghetti is a favorite for kids and adults. A delicious casserole that can be made ahead of time. Or double the recipe and make one in an aluminum foil pan, wrap it tightly, and freeze it, or give it to a friend. This cheesy chicken spaghetti is pure comfort food casserole and is excellent any time of the week.

Ingredients you'll need

Note: This is an overview of the ingredients. You'll find the full measurements and instructions in the recipe card (printable) at the bottom of the page.

📋 Ingredient notes

• Spaghetti: The spaghetti is uncooked as it will cook in the skillet.
• Cooked chicken: Dice or shred any leftover grilled chicken or rotisserie chicken.
• Cream of chicken soup: The base of the cream sauce, cream of mushroom soup can be substituted.
• Cream cheese: Adds extra creaminess.
• Milk
• Italian seasoning: The perfect seasoning to go with pasta.
• Shredded cheddar cheese: Goes amazingly well with spaghetti.
• Hot water: Added to cook the pasta with the sauce.
• RoTel tomatoes

Before you begin: essential tools

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• Large skillet

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Step by step: instructions

Note: This is an overview of the instructions. The detailed instructions are in the printable recipe card below.

1. Preheat the oven to 350°F. In a deep skillet add chicken soup, RoTel, milk, hot water, cream cheese and Italian seasoning.
2. Turn heat on medium high and whisk everything together.
3. When it starts to boil, add in spaghetti.
4. Cover and let it cook for 15 minutes.

5. Uncover and stir the spaghetti with a spoon to break them apart and keep them from sticking together.
6. Stir in chicken, and continue to cook for 5 more minutes until the pasta is cooked al dente.

7. If your skillet is oven safe, then sprinkle cheese on top and pop in the oven for 5-10 minutes until the cheese melts.
8. If not then spray a 13x9 casserole dish with cooking oil and pour the spaghetti chicken mixture in. Sprinkle with cheese and place in the oven until the cheese melts.

Adaptable recipe – make it your own!

• Switch out the chicken for turkey or even ground beef.
• Add diced bell peppers or another favorite veggie.
• Swap out the cheddar for the one you like best like Mozzarella, Monterey Jack or Velveeta.
• Leave the chicken out to go with a meatless meal.

My notes

• If you do not want to use canned cream of chicken, use homemade Alfredo sauce and substitute boiling chicken broth for the boiling water.
• If you do not want to use canned RoTel or do not have it where you live, add ¼ cup finely diced green pepper and ½ cup finely diced tomatoes.
• You can also use a can of diced tomatoes in place of the RoTel with chilies.
• You can use mozzarella cheese instead of cheddar cheese.
• Use your favorite pasta, I find spaghetti or linguine are the best choices as it holds the cheesy sauce with each bite.

💬 FAQs

Do you love making cheesy, spicy recipes? If so, you will want to add this crockpot buffalo chicken mac and cheese to your meal plan.

Make Ahead

• Chicken spaghetti with RoTel is the perfect make-ahead meal. Make the casserole up until the point where you put it in the oven. Wrap tightly and store in your refrigerator until you're ready to reheat and serve.

What to serve with Spaghetti Chicken

• I’d strongly urge you to add a side of greens like Air Fryer Frozen Broccoli, Frozen Asparagus, or Mediterranean Roasted Vegetables.
• Then if you’re going all out, add a side of Air Fryer Garlic Bread, or if you want to blow the comfort food meter, add a side of Garlic Bread Pizza.

Try one of these cozy desserts

Storage and reheating

Refrigerate - Place cooled leftover chicken spaghetti in an airtight container and refrigerate for 3-4 days.

Freeze - This casserole is great for freezing. Allow to cool completely, then cover tightly with plastic wrap, then double foil layer. Freeze for up to 4 months.

Reheat - Thaw frozen casserole in fridge overnight, then remove plastic wrap. Cover with foil and reheat in a 350F oven until heated thoroughly and bubbly. Individual portions can be reheated in the microwave.

More comfort food recipes

• Creamy Tuscan chicken pasta is one of those recipes that you would want on repeat. A delicious home cooked meal with tons of flavors.
• This vegetarian orzo recipe works as a vegetarian meal or a side dish. Takes less than 30 minutes and goes very well with any meat you have.
• This creamy pasta bake has been a family favorite with its creamy bechamel layer and flavorful ground beef.
• Baked ziti with ground beef is a delicious and satisfying comfort food that is easy to make at home. This dish can be made ahead of time and reheated for an easy weeknight dinner option.

For my chicken lovers

• Delicious and satisfying tender chicken in rich creamy sauce, this easy marry me chicken recipe will leave you wanting more. A perfect dish for quick and easy weeknight meal.
• Chicken Frances recipe is an easy chicken dish that tastes great and is perfect for entertaining guests.
• Chicken Hash Brown Casserole is an easy, comfort food casserole you can whip up in minutes. A family favorite chicken and potato casserole that's also perfect for busy weeknights.

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